Endocrine Abstracts

Introduction: 131I therapy in patients with papillary thyroid carcinomas (PTC) ≤2 cm and without extrathyroidal extension (T1) depends on multifactorial analysis: age, multifocality, histological criteria, lymph node or systemic metastasis. The study purposes were analyze PTC-T1 and compare the groups treated only with surgery vs combined therapy (surgery and 131I).Methods: Retrospective analysis of clinical files of PTC-T1 pa...

Introduction: The aging population brought new challenges in several diseases. Pituitary tumors are usually not related with elderly, although the rise in life expectancy has allowed its diagnosis in unusual age groups.Aim: To describe the pituitary tumors diagnosed in patients with age ≥ 80 yearsMethods: Retrospective observational study which included 23 patients with pituitary tumors with age ≥ 80 years observed in c...

Introduction: Graves’ disease (GD) hyperthyroidism is caused by autoantibodies against TSH receptor (TRAb). Three varieties of TRAb are now recognized: stimulating (TSI), blocking and neutral antibodies. Current TRAb immunoassays detect and quantify serum immunoglobulins that interact with the TSH receptor but without discriminating their function. An automated immunoassay for the detection and quantification of TSI is available.Objective: Our study...

Introduction: Congenital Adrenal Hyperplasia (CAH) results from enzymatic defects caused by autossomal recessive hereditary mutations characterized by deficient cortisol synthesis and, in most cases, increased androgen synthesis. 90–95% of the cases are originated by deficits in 21-hydroxylase and, in about 75% of the cases, there is evidence of mineralocorticoid deficiency.Case report: A 37-year-old patient was referred to an Endocrinology departm...

Introduction: Addison Disease is a rare condition with an estimated incidence in the developed world of 0.8 cases per 100 000 population. It is associated with relevant morbidity and mortality rates, but once the diagnosis is made it can be easily managed. When Addison Disease is associated with other autoimmune diseases, the diagnosis of polyglandular autoimmune syndrome can be set. The recognition of symptoms and signs can be challenging and clinicians should be aware of aty...

Osteoporosis and diabetes mellitus type 2 (DM2) have severe health consequences, with high morbidity and mortality risks.Aims: To study the differences of the sex steroid hormones levels and the free androgen index (FAI) in DM2 men with low BMD and osteoporosis and their relationships with BMD.Materials and methods: In 317 men with DM2, the BMD (g/cm2) was evaluated at the lumbar spine (L1-L4), at t...